Arsenal host rivals Manchester United, in a pivotal Premier League clash with both sides striving to finish in the top four and qualify for the Champions League.
The two sides are separated by just four points, whilst the Gunners still have a game in hand, so the pressure will be on both teams to claim a vital three points.
There was no separating the teams when they met at Old Trafford earlier in the season, with a late equaliser from Olivier Giroud goal ensuring a 1-1 draw – and it looks set to be another close battle between two giants of English football.
Arsene Wenger has guided his Arsenal team to a Champions League place in each of his 21 years at the club, but he will have to get the better of his old nemesis Jose Mourinho in order to keep that record intact. Wenger has never beaten a Mourinho side in the Premier League in 12 attempts, with his only success coming in the Community Shield in 2015.
Manchester United have a European semi-final to look forward to next month, and in the league they will be looking to extend an impressive 24 match unbeaten run.
However they arrive at the Emirates with an ever growing number of absentees. Zlatan Ibrahimovic, Marcos Rojo, Juan Mata, Chris Smalling, and Phil Jones will be joined by Timothy Fosu-Mensah on the injury list; with Marouane Fellaini also missing following his red card in the Manchester Derby.
Arsenal have rediscovered some much needed form and confidence after booking a place in the FA Cup final, and returned to winning ways in the league with a 1-0 win over Leicester.
The hosts will again be without Santi Cazorla, David Ospina, Shkodran Mustafi and Lucas Perez.